Immunoglobulins are highly diverse protein sequences that are processed and presented to T-cells by B-cells and other antigen presenting cells. We examined a large dataset of immunoglobulin heavy chain variable regions (IGHV) to assess the diversity of T-cell exposed motifs (TCEM). TCEM comprise those amino acids in a MHC-bound peptide which face outwards. surrounded by the MHC histot... https://www.thesportsshopkingswinfordes.shop/product-category/printing/