Polycomb group (PcG) proteins bind to and repress genes in embryonic stem cells through lineage commitment to the terminal differentiated state. PcG repressed genes are commonly characterized by the presence of the epigenetic histone mark H3K27me3. catalyzed by the Polycomb repressive complex 2. Here. https://www.roneverhart.com/Slate-Digital-VCC-Virtual-Console-Collection-p32717/