The RpoS sigma factor protein of Escherichia coli RNA polymerase is the master transcriptional regulator of physiological responses to a variety of stresses. This stress response comes at the expense of scavenging for scarce resources. causing a trade-off between stress tolerance and nutrient acquisition. This trade-off favors non-functional rpoS alleles in nutrient-poor environments. https://www.markbroyard.com/hot-sale-us-topo-7-5-minute-map-for-sunken-lake-mi-supply-limited-grab/
Compensatory evolution of gene regulation in response to stress by Escherichia coli lacking RpoS.
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